CatalogNumber: 21220 |
GeneSymbol: ER,ESR,ESR1,NR3A1 |
Description: Anti-RasRabbitPolyclonalAntibody |
Background: Estrogenreceptor(ER)isamemberofthenuclearhormonefamilyofintracellularreceptors.Therearetwodifferentformsoftheestrogenreceptor,usuallyreferredtoasαandβ,eachencodedbyaseparategenes(ESR1andESR2,respectively).Uponactivationbyestrogen,theestrogenreceptorisabletobindtoDNAandregulatetheactivityofmanydifferentgenes.DysfunctionofEstrogenreceptorsareimplicatedtocausediseasessuchascancer(breastcancer),aging,andobesity. |
Immunogen: AsyntheticpeptidefromtheinternalregionofERα,humanorigin. |
Applications: ELISA,WB,IHC |
RecommendedDilutions: ELISA:1:1000-1:5000WB:1:1000-1:2000IHC:1:50-100 |
Concentration: 1mg/ml |
Host: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Isotype: |
Purity: Purifiedfromserum |
Storagebuffer: |
Preservative: no |
Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
SpeciesReactivity: RecognizesERαproteinfromvertebrates. |
StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet: ![]() |
Westernblot: |
![]() | WesternblotanalysisofHis-ERαprotein.His-taggedERprotein(aminoacids1-300,Cat.#10251)wasblottedwiththepolyclonalanti-ER1antibody(Cat.#21220). |
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