NewEast/Estrogen Receptor 1 [21220][100 µL]/21220

CatalogNumber:  21220

GeneSymbol:  ER,ESR,ESR1,NR3A1

Description:  Anti-RasRabbitPolyclonalAntibody

Background:  Estrogenreceptor(ER)isamemberofthenuclearhormonefamilyofintracellularreceptors.Therearetwodifferentformsoftheestrogenreceptor,usuallyreferredtoasαandβ,eachencodedbyaseparategenes(ESR1andESR2,respectively).Uponactivationbyestrogen,theestrogenreceptorisabletobindtoDNAandregulatetheactivityofmanydifferentgenes.DysfunctionofEstrogenreceptorsareimplicatedtocausediseasessuchascancer(breastcancer),aging,andobesity.

Immunogen:  AsyntheticpeptidefromtheinternalregionofERα,humanorigin.

Applications:  ELISA,WB,IHC

RecommendedDilutions:  ELISA:1:1000-1:5000WB:1:1000-1:2000IHC:1:50-100

Concentration:  1mg/ml

Host:  Rabbit

Format:  Liquid

Clonality:  Polyclonal

Isotype:

Purity:  Purifiedfromserum

Storagebuffer:

Preservative:  no

Constituents:  PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol

SpeciesReactivity:  RecognizesERαproteinfromvertebrates.

StorageConditions:  Storeat-20°C.Avoidfreeze/thawcycles

DownloadDatasheet:

Westernblot:

WesternblotanalysisofHis-ERαprotein.His-taggedERprotein(aminoacids1-300,Cat.#10251)wasblottedwiththepolyclonalanti-ER1antibody(Cat.#21220).

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