| CatalogNumber: 21220 |
| GeneSymbol: ER,ESR,ESR1,NR3A1 |
| Description: Anti-RasRabbitPolyclonalAntibody |
| Background: Estrogenreceptor(ER)isamemberofthenuclearhormonefamilyofintracellularreceptors.Therearetwodifferentformsoftheestrogenreceptor,usuallyreferredtoasαandβ,eachencodedbyaseparategenes(ESR1andESR2,respectively).Uponactivationbyestrogen,theestrogenreceptorisabletobindtoDNAandregulatetheactivityofmanydifferentgenes.DysfunctionofEstrogenreceptorsareimplicatedtocausediseasessuchascancer(breastcancer),aging,andobesity. |
| Immunogen: AsyntheticpeptidefromtheinternalregionofERα,humanorigin. |
| Applications: ELISA,WB,IHC |
| RecommendedDilutions: ELISA:1:1000-1:5000WB:1:1000-1:2000IHC:1:50-100 |
| Concentration: 1mg/ml |
| Host: Rabbit |
| Format: Liquid |
| Clonality: Polyclonal |
| Isotype: |
| Purity: Purifiedfromserum |
| Storagebuffer: |
| Preservative: no |
| Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
| SpeciesReactivity: RecognizesERαproteinfromvertebrates. |
| StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet: ![]() |
| Westernblot: |
![]() | WesternblotanalysisofHis-ERαprotein.His-taggedERprotein(aminoacids1-300,Cat.#10251)wasblottedwiththepolyclonalanti-ER1antibody(Cat.#21220). |
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