CatalogNumber: 26364-1 |
GeneSymbol: BRCA2,BRCC2,FAD1,FCD,BROVCA2,PNCA2 |
Description: Anti-BRCA2(352-643)MouseMonoclonalAntibody |
Background: BRCA2isahumantumorsuppressorgene.Itsprotein,alsocalledbythesynonymbreastcancertype2susceptibilityprotein,isresponsIBLeforrepairingDNA.MutationsofBRCA2cancauseanincreasedriskofbreastcancer.Inadditiontobreastcancerinmenandwomen,mutationsinBRCA2alsoleadtoanincreasedriskofovarian,Fallopiantube,prostate,andpancreaticcancers,aswellasmalignantmelanoma. |
Immunogen: PurifiedBRCA2(352-643)protein,humanorigin. |
Applications: ELISA,WB,IHC |
RecommendedDilutions: ELISA:1:1000-1:2000WB:1:500-1:1000IHC:1:50-1:100 |
Concentration: 1mg/ml |
Host: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: |
Purity: Purifiedfromascites |
Storagebuffer: |
Preservative: no |
Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol |
SpeciesReactivity: RecognizesBRCA2(352-643)ofvertebrates. |
StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles |
DownloadDatasheet: |
Westernblot: |
WesternblotanalysisofrecombinantBRCA2proteins.PurifiedHis-taggedBRCA2(352-643)protein(lane1),His-taggedBRCA2(1475-1748)protein(lane2),His-taggedBRCA2(2213-2543)protein(lane3)andHis-taggedBRCA2(2793-3030)protein(lane4)wereblottedwithanti-BRCA2(352-643)monoclonalantibody(Cat.#26364-1). |
Immunofluorescence: |
ImmunofluorescenceofcellsexpressingBRCA2(352-643)proteinwithanti-BRCA2(352-643)antibody.HEK293TcellswastransfectedwithpCDNA3-GFP-BRCA2(352-643)plasmid,thenfixedandstainedwithanti-BRCA2(352-643)monoclonalantibody(Cat.#26364-1). |
RelatedProducts | |||||
Catalog# | Name | Size | Price | DataSheet | |
26364-1 | Anti-BRCA2(352-643)MouseMonoclonalAntibody | 100μL | $495 | ||
26364-2 | Anti-BRCA2(1475-1748)MouseMonoclonalAntibody | 100μL | $495 | ||
26364-3 | Anti-BRCA2(2213-2543)MouseMonoclonalAntibody | 100μL | $495 | ||
26364-4 | Anti-BRCA2(2793-3030)MouseMonoclonalAntibody | 100μL | $495 |
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