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NewEast/Active Gα13-GTP [26902][30 µL]/26902,NewEastBio,,NewEastBio,NewEast Biosciences,+,,Array.Array.Array蚂蚁淘厂家直采.
主营:专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。
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NewEast/Active Gα13-GTP [26902][30 µL]/26902

NewEast/Active Gα13-GTP [26902][30 µL]/26902
  • NewEast/Active Gα13-GTP [26902][30 µL]/26902
商品介绍

CatalogNumber:  26902
GeneSymbol:  Gna13
Description:  Anti-ActiveGα13-GTPMouseMonoclonalAntibody
Background:  HeterotrimericGproteinsareessentialcellularsignaltransducers.Gα13isoneoftheGproteinsthatcouldmediatecellmigrationandangiogenesis.OtherbiochemicalandphysiologicalfunctionsofGα13arebeingexplored.
Immunogen:  RecombinantfulllengthactiveGα13protein
Applications:  IP,IHC
RecommendedDilutions:  1µgfor1~2mgtotalcellularproteinsforIP;                                                   1:100dilutionforIHC
Concentration:  1mg/ml
Host:  mouse
Format:  Liquid
Clonality:  Monoclonal
Isotype:  IgG2b
Purity:  Purifiedfromascites
Storagebuffer:
Preservative:  no
Constituents:  PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol
SpeciesReactivity:  Anti-activeGα13monoclonalantibodyrecognizesactiveGα13ofvertebrates.
StorageConditions:  Storeat-20°C.Avoidfreeze/thawcycles
DownloadDatasheet:  
Immunoprecipitation/Westernblot:  
IP/WBanalysisofactiveGα13proteins.PurifiedGα13proteinsweretreatedwithGDP(lane1)orGTPGTPγS(lane2).Afterimmunoprecipitationwithanti-activeGα13-GTPmousemonoclonalantibody(Cat.#26902),theseproteinswereseparatedbySDS/PAGEandwesternblottedwithanti-Gα13mousemonoclonalantibody(Cat.#26004).
Immunohistochemistry:  
StainingofMEFcells(treatedwithPDGF)withanti-Gα13-GTPmonoclonalantibodyshowingthelocalizationofGα13-GTPintheleADIngedgeofmigratingcells.
 
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13MouseMonoclonalAntibody">26004Anti-Gα13MouseMonoclonalAntibody 100μL $239   
13RabbitPolyclonalAntibody">21005Anti-Gα13RabbitPolyclonalAntibody 100μL $219   
品牌介绍

NewEastBio我们已经开发了一项专有技术(正在申请专利),以生产与GTP结合的G蛋白的单克隆抗体。抗体应比结合GDP的蛋白更好地识别纯化的结合GTP的G蛋白(至少10倍)。我们可以利用该技术为您的特殊G蛋白生成抗体。活性G蛋白抗体的成本为10,000美元。但是,我们保留将抗体作为我们的产品销售的权利。

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Publications:
1.  Resistancetoinhibitorsofcholinesterase-8A(Ric-8A)iscriticalforgrowthfactorreceptor-inducedactincytoskeletalreorganization    JBiolChem.2011Sep2;286(35):31055-61
2.  AgoNISTactivationoftheGprotein-coupledreceptorGPR35involvestransmembranedomainIIIandistransducedviaGalphaandbeta-arrestin-2    BrJPharmacol.2011Feb;162(3):733-48
3.  Gα12/13inhibitionenhancestheanti-cancereffectofbortezomibthroughPSMB5downregulation    Carcinogenesis(2010)
4.  SuppressionoftumorangiogenesisbyGalpha(13)haploinsufficiency    JBiolChem.2009Oct2;284(40):27409-15