货号：26923
抗体名：Rab7
抗体英文名：Rab7-GTPantibody
靶点：Rab7
浓度：1mg/ml
应用范围：IP、IHC、IF
宿主：Mouse
供应商：NewEastBio
数量：30000
级别：实验级
目录编号：26923
抗原来源：Mouse
保质期：两年
适应物种：脊椎动物
标记物：FITC
克隆性：是
保存条件：-20℃
形态：液体
亚型：IgG
免疫原：Mouse
规格：30μl
ActiveRab7-GTP[26923]
[30µL]		 
 
CatalogNumber:  26923
GeneSymbol:  RAB7
Description:  Anti-ActiveRab7MouseMonoclonalAntibody
Background:  Rab7belongstotheRabfamilyofsmallGTPases.Rab7islocatedinthelateendosome,lysosome,cytoplasmicvesicle,phagosomeandmelanosome.Itisinvolvedinthelateendocytictransportandcontributestothematurationofphagosomes.
Immunogen:  RecombinantfulllengthproteinofactiveRab7
Applications:  IP,IHC,IF
RecommendedDilutions:  
1µgfor~2mgtotalcellularproteinsforIP 
1:100dilutionforIHC,IF
Concentration:  1mg/ml
Host:  mouse
Format:  Liquid
Clonality:  Monoclonal
Isotype:  IgG
Purity:  Purifiedfromascites
Storagebuffer:
Preservative:  no
Constituents:  PBS(withoutMg2+ andCa2+),pH7.4,150mMNaCl,50%glycerol
SpeciesReactivity:  Anti-activeRab7antibodyrecognizesactiveRab7proteinsofvertebrates.
StorageConditions:  Storeat-20°C.Avoidfreeze/thawcycles
 
Immunoprecipitation/Westernblot: 
Rab7activationassay.Purifiedfull-lengthRab7proteinswereimmunoprecipitatedaftertreatedwithGDP(lane1)orGTPγS(lane2).Immunoprecipitationwasdonewiththeanti-activeRab7monoclonalantibody(Cat.No.26923).Immunoblotwaswithananti-Rab7polyclonalantibody(Cat.No.21069).
Publications:
1.  VASPpromotesTGF-βactivationofhepaticstellatecellsbyregulatingRab11dependentplasmamembranetargetingofTGF-βreceptors
    HepatologyVolume61,Issue1,pages361–374,January2015
2.  Rab5ActivityRegulatesGLUT4SortingintoInsulin-ResponsiveandNon-Insulin-ResponsiveEndosomalCompartments:APotentialMechanismforDevelopmentofInsulinResistance
    Endocrinology.2014Sep;155(9):3315-28
温馨提示：不可用于临床治疗。