弹性蛋白酶(猪胰)性状及用途
来自 : NewEastBio中国
发布时间:1628443803
货号: | 26309 |
抗体名: | CTNNB1(S45Y)抗体 |
抗体英文名: | CTNNB1(S45Y)antibody |
靶点: | Beta-catenin,CTNNB,Cateninbeta-1 |
浓度: | 1mg/ml |
应用范围: | ELISA,WB,IHC |
宿主: | Mouse |
供应商: | NewEastBio |
数量: | 30000 |
级别: | 实验级 |
目录编号: | 26309 |
抗原来源: | Mouse |
保质期: | 两年 |
适应物种: | 脊椎动物 |
标记物: | FITC |
克隆性: | 是 |
保存条件: | -20℃ |
形态: | 液体 |
亚型: | IgG |
免疫原: | AsyntheticpeptidefromtheinternalregionofCTNNB1whichincludesthemutationofS45Y,humanorigin. |
规格: | 100μl |
CTNNB1(S45Y)[26309] [100ul] | |
CatalogNumber: 26309 | GeneSymbol: Beta-catenin,CTNNB,Cateninbeta-1 | Description: Anti-CTNNB1(S45Y)MouseMonoclonalAntibody | Background: CTNNB1proteinisadualfunctionprotein.Itisasubunitofacomplexofproteinsthatfromadherensjunctions,whichareimportantfortheestablishmentandmaintenanceofepithelialcelllayersbyregulatingcellgrowthandadhesionbetweenadjacentcells.CTNNB1proteinalsopullsdoubledutyasanintracellularsignaltransducerintheWntsignalingpathway.MutationsofCTNNB1havebeenimplicatedinthepathogenesisofseveralcancers. | Immunogen: AsyntheticpeptidefromtheinternalregionofCTNNB1whichincludesthemutationofS45Y,humanorigin. | Applications: ELISA,WB,IHC | RecommendedDilutions: ELISA:1:1000-1:2000 WB:1:500-1:1000 IHC:1:50-1:100 | Concentration: 0.5mg/ml | Host: Mouse | Format: Liquid | Clonality: Monoclonal | Isotype: | Purity: Purifiedfromascites | Storagebuffer: | Preservative: no | Constituents: PBS(withoutMg2+andCa2+),pH7.4,150mMNaCl,50%glycerol | SpeciesReactivity: RecognizesS45Ymutant,butnotwild-typeCTNNB1ofvertebrates. | StorageConditions: Storeat-20°C.Avoidfreeze/thawcycles | DownloadDatasheet:  | Westernblot: |
 | WesternblotanalysisofrecombinantCTNNB1(S45Y)andwildtypeproteins.PurifiedHis-taggedCTNNB1(S45Y)protein(lane2)andcorrespondingwild-typeprotein(lane1)wereblottedwithanti-CTNNB1(S45Y)monoclonalantibody(Cat.#26309). |
ImmunofluorescenceofcellsexpressingCTNNB1proteinswithanti-CTNNB1(S45Y)antibody.HEK293TcellsweretransfectedwithpCDNA3-GFP-CTNNB1(S45Y)plasmid,pCDNA3-GFP-CTNNB1(WT)plasmidorpCDNA3-GFP-CTNNB1(S45F)plasmid,thenfixedandstainedwithanti-CTNNB1(S45Y)monoclonalantibody(Cat.#26309). |
|
温馨提示:不可用于临床治疗。
本文链接: http://neweastbio.ebiomall.cn/show-769457.html