Catalog Number:  26166

Gene Symbol:  CTNNB1, CTNNB

Description:  Anti-β-catenin (G48D) Mouse Monoclonal Antibody

Background:  Beta-catenin (or β-catenin) is a protein that in humans is encoded by the CTNNB1 gene. β-catenin is a subunit of the cadherin protein complex and also acts as an intracellular signal transducer in the Wnt signaling pathway. Deregulation of beta-catenin signaling is an important event in the genesis of a number of malignancies, such as colon cancer, melanoma, hepatocellular carcinoma, ovarian cancer, endometrial cancer, medulloblastoma pilomatricomas, and prostate cancer.

Immunogen:   A synthetic peptide from the internal region of β-catenin which includes the mutation of G48D, human origin.

Applications:  ELISA, WB, IF, IHC

Recommended Dilutions:   ELISA:1:1000-1:5000 WB: 1:500-1:2000 IHC: 1:50-1:100

Concentration:   1 mg/ml

Host:  Mouse

Format:   Liquid

Clonality:   Monoclonal

Isotype:

Purity:   Purified from ascites

Storage buffer:

Preservative:  no

Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity:   Recognizes β-catenin (G48D), but not wild type β-catenin protein from vertebrates.

Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles

Download Datasheet:

Western blot:

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